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Semaglutide
Weekly GLP-1. Care, coaching and shipping included.
Get startedHome / Compounded semaglutide storage
Cold at home. Cold on the road.
Compounded semaglutide storage: your label, warm deliveries and travel
Keep compounded semaglutide in the fridge at 36°F to 46°F, in its box, unless your label says otherwise, and never let it freeze. Use an opened vial within 28 days or by its beyond-use date. Wegovy’s room-temperature rules don’t apply to vials.
- Wegovy’s pen rules aren’t your vial’s rules
- A vial’s life is set by days, not by what’s left
- Flying? Carry-on, insulated, declared
Published by NexLifeLegitScript-certifiedUpdated October 9, 2026Medically reviewed by the NexLife clinical team, led by Adam Kennah, MD (NPI 1144260043)
Semaglutide storage at a glance
- Fridge
- 36°F to 46°F, in its box, unless your label says otherwise
- Opened vial
- Use within 28 days, or by the beyond-use date if sooner
- Traveling
- Carry-on only, insulated, with a cold pack
- Warm or frozen
- Don’t use it. Call or text us
- Wegovy’s 28-day pen rule
- For Wegovy pens, not compounded vials
Not sure about your vial? Text us a photo at (949) 818-8000. We check with the pharmacy for you.
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The common mix-up
Wegovy rules vs. your vial.
It’s easy to borrow Wegovy’s storage rules, because they’re printed everywhere. They don’t transfer. Here’s why, side by side.
| Wegovy pen | Compounded vial | |
|---|---|---|
| Who sets the rules | Novo Nordisk, from stability testing reviewed by the FDA | The pharmacy that prepared it, on your label |
| Out of the fridge | Up to 28 days at 46°F to 86°F, before the cap comes off | Only if your label allows it |
| After first use | Single-use pen, then discarded | Up to 28 days, or the beyond-use date if sooner |
| Freezing | Don’t freeze; don’t use if frozen | Don’t freeze; don’t use if frozen |
Wegovy storage from its FDA-approved prescribing information. Compounded semaglutide isn’t FDA-approved.
From the pharmacy to your fridge, done right.
Compounded semaglutide comes with its own storage rules, printed by the pharmacy that made it. Here’s how to follow them.
- Your label wins. The pharmacy’s storage directions and beyond-use date are the ones to follow.
- Pens aren’t vials. Wegovy pen rules don’t carry over to a compounded vial.
- Weather happens. A hot porch or a frozen stoop can change what you should do next.
One number to call. We handle the rest.
- Something looks off? Call or text us first. We follow up with the pharmacy for you.
- Shipped fast. Our partner pharmacy usually ships within 1 to 2 business days, discreetly packed.
- $139 at every dose. Semaglutide, from 0.25 mg to 2.4 mg, with no membership.
Real people, real answers. A package arrived warm, or a vial looks wrong? Tell us first. Call or text (949) 818-8000, 24/7.
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Opened vials
How long one vial really lasts.
Days, not doses, set the limit. Once you puncture a multiple-dose vial, the clock starts. The FDA recommends discarding it after 28 days, even if there’s medication left, because every puncture adds a little contamination risk.
Your dose decides how much you use. Early on, at low doses like 0.25 mg a week, a vial may hold more than four weeks of medication. That extra doesn’t make it safe to stretch past day 28.
Concentration changes the math. Compounded vials don’t all hold the same strength, so the same dose can be a different volume in a different vial. Go by the milligrams and the instructions your provider gives you, not by units you used before.
New vial looks different from your last one, or the instructions changed? Text us at (949) 818-8000 before your next dose. We check with your provider and the pharmacy and come back to you.
On the road
Traveling with semaglutide.
Pack it in your carry-on
Cargo holds can get cold enough to freeze a vial, and checked bags get lost. Keep it with you.
Use an insulated case and a cold pack
TSA allows medically necessary gel ice packs in reasonable amounts, even when they’re melted or slushy.
Tell the officer at screening
TSA allows larger amounts of medically necessary liquids. Declare the vial and your supplies at the checkpoint.
Back in a fridge on arrival
Hotel minibars can run warm or freeze things. Ask for a medical fridge if the room has none.
Two medications.
One flat price each.
Both are prepared by state-licensed 503A partner pharmacies and shipped free. Your provider helps you decide which one fits.
$169/mo
Tirzepatide
Weekly and dual-action. Care, coaching and shipping included.
Get startedWhat’s inside every plan
- Semaglutide: compounded, acts on the GLP-1 pathway, taken once a week
- Tirzepatide: compounded, acts on two hormone pathways (GIP and GLP-1), taken once a week
- Prepared by state-licensed 503A partner pharmacies
- A licensed provider who reviews your history and follows your dose
- A personalized nutrition plan and a 1:1 coaching call
- Free expedited shipping; orders usually ship within 1 to 2 business days
- 24/7 support from real people, plus physician access during clinical hours
- HSA and FSA cards accepted, and Klarna or Afterpay at checkout
- Prefer no injections? Ask about the sublingual tablet, at its own flat price
Prescription required. Compounded medications are not FDA-approved. On 12-month plans: $139 a month for tirzepatide, $119 for semaglutide, still the same at every dose. Prices checked October 7–8, 2026.
Your dose goes up.
Your price doesn’t.
No membership, no dose surcharges, no surprises. One flat, all-inclusive monthly price at every dose.
| Month one | Month two | Month three | Every month after | |
|---|---|---|---|---|
| Semaglutide | $139 | $139 | $139 | $139 |
| Tirzepatide | $169 | $169 | $169 | $169 |
Paying less somewhere else? Send us a receipt from another licensed U.S. telehealth provider and we’ll match your regular monthly price. See the terms
Month-to-month plan, all-inclusive. Longer plans cost less and stay flat. Tirzepatide is $159, $149 and $139 a month on 3-, 6- and 12-month plans. Semaglutide is $132, $125 and $119.
What would you pay with NexLife?
Tap where you are now. We’ll show your NexLife price next to it, or tell you we’ll match it.
Pick one above to see your price.
Not today?
Prices from each provider, checked October 7–8, 2026. Brand-name and compounded medications are different products; compounded medications are not FDA-approved. †Price Match Guarantee terms apply.
The NexLife Price Match Guarantee
Keep your price.
Upgrade your care.
Already on compounded tirzepatide or semaglutide? Bring your price to NexLife. If you pay less with another licensed U.S. telehealth provider, we match your regular monthly price for as long as your plan stays active.† You keep your price, and you gain a provider who follows your dose, a personal nutrition plan, a 1:1 coaching call and real people who answer 24/7.
- 1Send a receipt from the last 60 days
- 2A NexLife provider reviews your prescription
- 3Pay your matched price, at every dose
Locked while your plan is activeSame price at every doseNo membership fee
†NexLife Price Match Guarantee: for new members switching from a licensed U.S. telehealth provider with an active prescription for compounded tirzepatide or semaglutide. Send a receipt from the last 60 days and we match your regular all-in monthly price on the month-to-month plan, for the same medication (medication plus required fees; not first-month offers, coupons or prepaid multi-month rates), for as long as your plan stays active. A NexLife provider must determine that treatment is right for you. Not open to people with Medicare, Medicaid or TRICARE coverage. Full terms.
Support
When something’s off, one call does it.
Late, warm or damaged delivery
Keep everything, don’t use the vial, and call or text us. We contact the pharmacy.
Frozen, cloudy or particles
Don’t inject it. We confirm with the pharmacy and arrange what comes next.
Running out before day 28
Tell us early. We time your next shipment around your dose.
Label doesn’t match
Stop and call or text us. We check it against your prescription.
One number for everything.
A question about your vial, a package that arrived warm, a dose that feels wrong: call or text us 24/7 at (949) 818-8000. Real people answer. We follow up with the pharmacy for you and get back to you. You never have to chase anyone.
Semaglutide storage: your questions, answered
How should I store compounded semaglutide?
Follow the label from your pharmacy. Most compounded semaglutide vials go in the refrigerator at 36°F to 46°F (2°C to 8°C), in their box, never frozen. Your label’s storage line and beyond-use date are the rules that apply to your vial.
Can compounded semaglutide be left out of the fridge?
Only if your label says so, and only for as long as it says. Wegovy pens can be kept at 46°F to 86°F for up to 28 days before the cap comes off, but that was tested for Wegovy, not for a compounded vial.
How long is a vial of compounded semaglutide good for after opening?
Up to 28 days after you first puncture it, as the FDA recommends for multiple-dose vials, or until the beyond-use date on the label if that’s sooner. Discard it then, even if medication is left.
Can I fly with compounded semaglutide?
Yes. Keep it in your carry-on, never in checked bags, in an insulated case with a cold pack. TSA allows medically necessary liquids in larger amounts and medically necessary gel ice packs even when they’re slushy; tell the officer at screening.
What if my semaglutide arrived warm or froze?
Don’t use it. Keep the vial and packaging, and call or text us at (949) 818-8000, 24/7. We contact the pharmacy for you and come back with the next step.
Does compounded semaglutide need to stay in its box?
Keep it in the original box unless your label says otherwise. The box protects it from light and from knocks in the fridge.
Important safety information
Compounded tirzepatide and semaglutide are not FDA-approved, and the FDA hasn’t reviewed them for safety, effectiveness or quality. Both medicines may cause thyroid tumors, including cancer: don’t use either if you or a family member has had medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).
Read the full safety information
In studies with rodents, both medicines caused thyroid tumors; it isn’t known whether they cause them in people. Tell your provider if you notice a lump or swelling in your neck, hoarseness, trouble swallowing or shortness of breath.
Serious side effects can include inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar (especially with insulin or sulfonylureas), kidney problems from dehydration, severe stomach problems, serious allergic reactions, vision changes in people with type 2 diabetes, and depression or thoughts of suicide. Tell your care team before any surgery or procedure that uses anesthesia or deep sedation. Don’t combine either medicine with other GLP-1 medicines.
Tirzepatide can make birth control pills less effective: use another method for 4 weeks after you start and after each dose increase. Semaglutide should be stopped at least 2 months before a planned pregnancy. Tell your provider if you’re pregnant, planning to be, or breastfeeding.
This is a summary, not the complete safety information. Read the full Prescribing Information for FDA-approved tirzepatide (Zepbound) and semaglutide (Wegovy), and talk with your provider. You can report side effects to the FDA at 1-800-FDA-1088 or fda.gov/medwatch.
Who checked this page
Adam Kennah, MDMedical Director, NexLife · Board-certified in emergency medicine · NPI 1144260043
Leads the NexLife clinical team, which medically reviewed this page on October 8, 2026.
NexLife editorial teamResearch and pricing
Checked the FDA’s storage guidance, Wegovy’s labeling and TSA’s medical travel rules on October 8, 2026.
- Every fact, sourced. Each price and rule links to the page it comes from.
- How we make money. NexLife is a telehealth provider. We earn revenue when people join NexLife.
- Corrections, fast. See something wrong or out of date? Email care@nexlife.us and we’ll fix it.
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Sources
- U.S. Food and Drug Administration. FDA’s concerns with unapproved GLP-1 drugs used for weight loss.
- Novo Nordisk. Wegovy (semaglutide) prescribing information.
- U.S. Pharmacopeia. USP General Chapter <797> Pharmaceutical Compounding: Sterile Preparations.
- Transportation Security Administration. What can I bring? Medical.
- Transportation Security Administration. What can I bring? Gel ice packs.
- NexLife. Compounded semaglutide plans.
- Eli Lilly and Company. Zepbound (tirzepatide) prescribing information.
- LegitScript. Certification lookup for nexlife.us.
- NexLife. Compounded tirzepatide plans.