Medically reviewed by Adam Kennah, MD, Medical Director, NexLife
Quick answer
Across the 8 online semaglutide providers we compared on September 21, 2026, the all-in monthly cost on a month-to-month plan runs from $139 to $498. NexLife (our program) and Mochi start lowest at $139 a month. NexLife stays $139 at every dose, while Mochi's medication price rises with dose. Hims offers FDA-approved Wegovy from $298 a month and Ro from $348 once the required membership is added. Compounded semaglutide is not FDA-approved.
Lowest all-in price we found: $139 a month (NexLife at every dose, Mochi at the starting dose)
Same price at every dose: NexLife ($139) and Eden ($198, including its $99 membership)
Brand-name Wegovy: Hims from $298 and Ro from $348 a month all-in, and Ro reaches $498 at the 2.4 mg dose
Mainly compounded: NexLife, Mochi, Eden and Remedy Meds. Brand-name Wegovy only: Ro, Hims, WeightWatchers Clinic and LifeMD
Best for help with insurance: Ro, WeightWatchers Clinic and LifeMD
Compare the all-in cost every time: medication, membership, shipping and dose increases
The 8 best semaglutide providers, reviewed
Every program here requires a prescription from a licensed clinician. The differences are in what you pay, what you receive and who you can reach.
1
Our top pick, and yes, it's ours
NexLife
Our pick
$139/moall-in, at every dose
NexLife charges one all-inclusive price whatever dose you're prescribed: $139 month to month, or as low as $119 a month on a 12-month plan, with no membership fee. The semaglutide is compounded by U.S.-licensed 503A pharmacies, and NexLife also offers a microdose option and a no-injection sublingual tablet at their own flat prices.
Included at no extra cost
Personalized nutrition plan
1:1 call with a certified wellness coach
Provider review and medical guidance
Longer plans cost less per month
Monthly$139/mo
3 months$132/mo
6 months$125/mo
12 months$119/mo
Starting price
$139/mo
At highest dose
$139/mo
Fees
No membership or contracts
Medication
Compounded semaglutide from U.S.-licensed 503A pharmacies
Visits
Online in all 50 states, by live video or provider review
Payment
HSA and FSA accepted, with itemized receipts and a letter of medical necessity. Financing available
Shipping
Free expedited shipping, typically 1 to 2 business days, discreetly packaged
Support
24/7 support, with licensed providers, dietitians and care coordinators
What we like
One flat price at every dose, with no membership or contract
Provider review, a nutrition plan and a 1:1 coaching call are included
Cancel anytime, and longer plans drop to $119 a month
Every batch is tested by an independent lab for potency and sterility before it ships
What to know
Semaglutide here is compounded, which means it isn't FDA-approved. If you want brand-name Wegovy or Ozempic, choose a provider that prescribes it
Board-certified obesity medicine doctors and registered dietitians
Insurance check, plus brand-name options
What to know
Membership is billed separately at $79 a month
Medication is priced by dose, and higher-dose prices aren't on the page we checked
Compounded, so not FDA-approved
Price, medication and support details
Starting price
$139/mo
At highest dose
Not published
Fees
Includes the $79 a month membership. The first month of membership is $39. Medication starts at $60 and is priced by dose
Medication
Compounded semaglutide. Brand-name Wegovy is listed from $199 a month
Visits
Visits with a board-certified provider you choose
Payment
Checks your insurance options
Shipping
Not stated on its site
Support
24/7 care team, coaching and a registered dietitian
3
Eden
Flat price, plus a membership
$198/moall-in, at every dose
What we like
Medication price is the same at every dose, with no long-term contract
Free expedited shipping and 24/7 care team messaging
Also lists brand-name options
What to know
A membership is required on top: $39 for the first month, then $99 a month
Compounded, so not FDA-approved
Price, medication and support details
Starting price
$198/mo
At highest dose
$198/mo
Fees
$99 medication plus a required $99 a month membership. The first month of membership is $39
Medication
Compounded semaglutide. Brand-name Wegovy is listed at $1,695 a month
Visits
Online visit with a licensed provider
Payment
No insurance needed. FSA and HSA eligible
Shipping
Free expedited shipping
Support
Unlimited 24/7 messaging with your care team
4
Hims
Brand-name with a 24/7 care team
$298/moall-in, to start
What we like
FDA-approved options, including Zepbound and the Wegovy pill
24/7 care team messaging, nutrition guidance and a smart scale are included
What to know
Membership is billed separately: $39 for the first month, then $149 a month
Its site says it isn't available in all 50 states
Price, medication and support details
Starting price
$298/mo
At highest dose
Not published
Fees
Includes the $149 a month membership. First month is $39
Medication
FDA-approved Wegovy, with the pill from $149 a month
Visits
Online intake reviewed by a licensed provider
Payment
Insurance not required. Medication is FSA and HSA eligible, the membership isn't
Shipping
Not stated on its site
Support
24/7 care team messaging, nutrition guidance and a smart scale
5
Ro
Best for insurance help
$348/moall-in to start, $498 at the highest dose
What we like
FDA-approved Wegovy at the manufacturer's cash price
Insurance concierge checks coverage and handles paperwork
$39 first-month membership is refunded if you aren't eligible
What to know
Two separate charges: medication plus a membership that's $149 a month on the monthly plan
The medication price rises with your dose
Price, medication and support details
Starting price
$348/mo
At highest dose
$498/mo
Fees
Includes the $149 a month membership on the monthly plan. First month is $39, and it drops to $74 a month if you prepay a year
Medication
FDA-approved Wegovy pen: $199 for the two starter doses with a limited-time offer, then $349. A Wegovy pill starts at $149
Visits
Online, with on-demand provider messaging
Payment
Free coverage check, and a concierge handles the paperwork
Shipping
Not stated on its site
Support
1:1 provider messaging, check-ins and coaching
6
WeightWatchers Clinic
Best for habit coaching
Price varies
What we like
FDA-approved medication paired with WeightWatchers' behavior program and workshops
An insurance coordinator works on coverage and prior authorizations
What to know
Membership runs on 6- or 12-month plans that renew automatically
Medication is billed separately
Price, medication and support details
Starting price
Price varies
At highest dose
Not published
Fees
Med+ membership is $74 to $84 a month on a 12- or 6-month plan, after a $25 first month. The medication price isn't on the page we checked
Medication
FDA-approved medications only, such as Zepbound and Wegovy
Visits
Telehealth visit with a board-certified clinician
Payment
An insurance coordinator handles prior authorizations and refills
Shipping
Delivered for many plans, otherwise sent to your pharmacy
Support
Care team, nutrition counseling, workshops and the WeightWatchers app
7
LifeMD
Labs and clinician visits included
Price varies
What we like
Clinician visits, coaching and lab work are included in the program fee
Helps check whether insurance will cover your medication
Cancel anytime
What to know
The $149 a month program fee doesn't include medication
Not open to people with Medicare, Medicaid or TRICARE coverage
Price, medication and support details
Starting price
Price varies
At highest dose
Not published
Fees
Program is $149 a month after a $39 first month. Medication isn't included, and its price isn't on the page we checked
Medication
FDA-approved Zepbound or Wegovy, sent to your pharmacy or mailed
Visits
Online visits with a licensed provider. Lab work may be required
Payment
Helps check whether insurance covers your medication. Not open to people with Medicare, Medicaid or TRICARE
Shipping
Not stated on its site
Support
Coaching and ongoing clinician check-ins
8
Remedy Meds
365-day money-back guarantee
Price not listed
What we like
Month to month, cancel anytime, HSA and FSA accepted
Unlimited clinician video calls and messaging
Says every batch passes four independent lab tests
What to know
No price on its home page, so you can't compare before the quiz
Compounded, so not FDA-approved
Price, medication and support details
Starting price
Price not listed
At highest dose
Not published
Fees
Its home page doesn't show a price. You see it after a short quiz
Medication
Compounded semaglutide, with brand-name options at retail pricing
Visits
Unlimited clinician video calls and messaging
Payment
HSA and FSA accepted
Shipping
Free, discreet shipping
Support
Care team 7 days a week, meal plans and a member community
How much does semaglutide cost per month at each provider?
Medication+membership+shipping+dose increases=what you actually pay
Most people move up in dose over the first few months, and some programs charge more when that happens. Each bar is the all-in monthly cost on a month-to-month plan, including any required membership. Dark is the starting dose, light is the highest dose. Where a provider doesn't publish a number, we say so instead of guessing. Prices as of September 21, 2026.
All-in monthly cost of semaglutide at each provider, checked September 21, 2026
Provider
All-in monthly cost
Medication type and fees
NexLife
$139/mo at every dose
Compounded. No membership or contracts
Mochi
$139/mo to start
Compounded. Includes the $79 a month membership. The first month of membership is $39. Medication starts at $60 and is priced by dose
Eden
$198/mo at every dose
Compounded. $99 medication plus a required $99 a month membership. The first month of membership is $39
Hims
$298/mo to start
Brand-name Wegovy. Includes the $149 a month membership. First month is $39
Ro
$348 to $498/mo
Brand-name Wegovy. Includes the $149 a month membership on the monthly plan. First month is $39, and it drops to $74 a month if you prepay a year
WeightWatchers Clinic
Price varies
Brand-name Wegovy. Med+ membership is $74 to $84 a month on a 12- or 6-month plan, after a $25 first month. The medication price isn't on the page we checked
LifeMD
Price varies
Brand-name Wegovy. Program is $149 a month after a $39 first month. Medication isn't included, and its price isn't on the page we checked
Remedy Meds
Price not listed
Compounded. Its home page doesn't show a price. You see it after a short quiz
Starting doseHighest dose
Why the gaps are so wide. Brand-name Wegovy programs cost more than compounded ones, and they aren't the same product. Wegovy is FDA-approved. Compounded semaglutide isn't, which means the FDA hasn't reviewed it for safety, effectiveness or quality. Decide which one you want before you compare prices.
NexLife is $139/mo, all-inclusive, same price at every dose.
Questions to ask any semaglutide provider, and how NexLife answers them
Put the same questions to every program on this list. Here are our answers, in plain terms.
Is the medication FDA-approved or compounded?
Compounded. It isn't FDA-approved, and it isn't Wegovy or Ozempic. A licensed provider decides whether it's appropriate for you.
What will I pay in month one, all in?
$139 on the monthly plan, with no membership, sign-up or hidden fees. That covers the provider review, medication, expedited shipping, a nutrition plan and a coaching call.
Does the price go up with my dose?
No. It's the same price at every dose.
Do I have to prepay or commit?
No. You can stay month to month and cancel anytime. Longer plans lower the monthly price: $132 on a 3-month plan, $125 on 6 months and $119 on 12.
Which pharmacy fills my prescription?
A U.S.-licensed 503A compounding pharmacy, chosen by your location and your provider's direction. Our pharmacy partners are named on our site, and you can verify each one through its state pharmacy board.
Who can I reach between visits?
Licensed providers oversee your care and support is available 24/7. Before you start, you can call or text (949) 818-8000.
What if it doesn't work for me?
If you complete six months as prescribed and lose less than 5% of your starting weight, you can request a refund of program fees. Medication costs aren't refundable, so the refund is only part of what you paid, and conditions apply. Read the full refund policy.
How we compared these semaglutide providers
We compared every provider on the points below, using only what each one publishes on its own website, checked on September 21, 2026. We don't give numeric scores. NexLife is listed first because it's our program and, in our view, the best value here. The rest are ordered by all-in starting cost, and the "best for" labels are our opinion. Spot something out of date? Tell us and we'll fix it.
Price and transparency
Is the full monthly cost clear up front? Does it cover medication, visits and supplies, and does it climb with your dose?
Clinical care
Who evaluates you, how you reach them, and how closely your dose and side effects are followed.
Medication and pharmacy
Which product you actually receive, which pharmacy dispenses it, and how plainly the provider says so.
Support
How quickly you get answers between visits, and who they come from.
Ease of use
Signing up, refills, shipping speed and how easy it is to cancel.
How semaglutide dosing steps up
With FDA-approved semaglutide for weight management, treatment starts at 0.25 mg once a week for four weeks so the body can adjust. The dose then steps up about every four weeks, through 0.5 mg, 1 mg and 1.7 mg, to a maintenance dose of 1.7 mg or 2.4 mg.2 Your prescriber sets your actual schedule, and a compounded prescription can follow a different one. Not everyone needs the highest dose.
0.25 mgStarter, weeks 1 to 4
0.5 mg
1 mg
1.7 mg
2.4 mgMaintenance dose
Semaglutide provider FAQ
How much does semaglutide really cost without insurance?
In our comparison, all-in monthly costs ran from $139 to $498 on a month-to-month plan, depending on the provider, your dose and whether the product is compounded or brand-name. Look past the starting price: some programs charge more as your dose goes up, and some add a membership fee. The cost section above shows each provider's price at the starting dose and at the highest dose as of September 21, 2026. Check what the price includes (medication, clinician visits, supplies, shipping) before you sign up.
Is compounded semaglutide the same as Wegovy or Ozempic, and does it work as well?
No, it isn't the same, and no provider can honestly promise it works as well, because it hasn't been tested that way. Compounded medications aren't FDA-approved, which means the FDA hasn't reviewed them for safety, effectiveness or quality. The FDA determined in early 2025 that the semaglutide shortage was over, which sharply limits when pharmacies can compound it.3 A pharmacy can still compound it for an individual patient when the prescriber decides a formulation different from the commercial product is needed. Ask any provider exactly which product you'll receive and which pharmacy dispenses it.
How can I check that a compounded semaglutide provider is legitimate?
Look for four things. The site should require a health assessment and a prescription from a licensed clinician. It should hold LegitScript certification, which you can confirm at legitscript.com. It should tell you which pharmacy fills your prescription, so you can look up that pharmacy's license with its state board of pharmacy. And it should say plainly that compounded semaglutide is not FDA-approved. Avoid anyone selling vials without a prescription or labeled for research use.
Am I likely to qualify?
Most programs use the same starting point as the FDA-approved medicines: a BMI of 30 or higher, or 27 or higher with a weight-related condition such as high blood pressure, type 2 diabetes or high cholesterol. A licensed clinician reviews your health history and makes the call, and not everyone who applies is prescribed treatment.
Do I need a prescription?
Yes. Semaglutide is prescription-only. Every provider on this list requires a health assessment, and a licensed clinician decides whether it's appropriate for you. Avoid any site that offers to sell it without one.
How much weight do people lose on semaglutide?
In the 68-week STEP 1 trial, adults with overweight or obesity who took semaglutide 2.4 mg alongside diet and exercise lost an average of about 15% of their body weight, compared with about 2% on placebo.1 The trial studied FDA-approved semaglutide. Compounded versions haven't been studied in trials like this one. Individual results vary.
What are the most common side effects?
Nausea, diarrhea, vomiting, constipation, stomach pain, headache and tiredness are the most common, especially while the dose is going up. Semaglutide also carries a boxed warning about thyroid C-cell tumors. Read the safety information below and go over your medical history with your clinician.
Can I switch providers if I've already started?
Usually, yes. A new provider will do its own assessment before prescribing. Have your current dose and start date handy, and don't change your dose without a clinician's guidance.
Is this ranking biased?
We publish this guide and we list ourselves first, so read it the way you'd read any company describing itself. What we can tell you is that every provider, including NexLife, was compared on the same points shown in how we compared, using only what each provider publishes. Compare for yourself before you decide.
What is semaglutide?
Semaglutide is a once-weekly injection that mimics GLP-1, a hormone that helps control appetite, fullness and blood sugar. It's the active ingredient in Wegovy, which the FDA approved for chronic weight management, and in Ozempic, approved for type 2 diabetes.
Important safety information
Compounded semaglutide is not FDA-approved. The FDA has not reviewed it for safety, effectiveness or quality. The risks below come from the labeling of FDA-approved semaglutide.
Semaglutide may cause tumors in the thyroid, including thyroid cancer. In studies with rodents, semaglutide caused thyroid tumors, and it isn't known whether it causes them in people. Don't use semaglutide if you or anyone in your family has had medullary thyroid carcinoma (MTC), or if you have multiple endocrine neoplasia syndrome type 2 (MEN 2). Tell your clinician if you notice a lump or swelling in your neck, hoarseness, trouble swallowing or shortness of breath.
Don't use semaglutide if you've had a serious allergic reaction to it. Serious side effects can include inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar (especially with insulin or sulfonylureas), kidney problems from dehydration, severe stomach problems, serious allergic reactions, vision changes in people with type 2 diabetes, an increased heart rate, and depression or thoughts of suicide. Tell your care team you take semaglutide before any surgery or procedure that uses anesthesia or deep sedation.
Don't take it with other semaglutide products or GLP-1 medicines. Semaglutide may harm an unborn baby, so stop it at least 2 months before a planned pregnancy, and tell your clinician if you're pregnant or breastfeeding.
This is a summary, not the complete safety information. Read the full Prescribing Information for FDA-approved semaglutide and talk with your clinician. You can report side effects to the FDA at 1-800-FDA-1088 or fda.gov/medwatch.
Published by NexLife. We're one of the providers listed here, and we compared ourselves on the same points as everyone else. See how we compared. The order and the "best for" labels are our opinion. Provider details come from each company's public website as of September 21, 2026 and can change, so confirm them before you enroll.
Pricing sources, all checked on September 21, 2026: nexlife.us; joinmochi.com; eden.health/treatment/glp-1-treatments; ro.co/weight-loss/pricing; hims.com/weight-loss; weightwatchers.com/us/weight-loss-medication; lifemd.com/weight-management; remedymeds.com.
This page is for general information and isn't medical advice. Only a licensed clinician can decide whether a prescription medication is right for you. Zepbound and Mounjaro are registered trademarks of Eli Lilly and Company. Wegovy and Ozempic are registered trademarks of Novo Nordisk A/S. Neither company, and none of the providers named here, is affiliated with NexLife or endorses this page. Provider names and icons belong to their owners.
Physician-led, LegitScript-certified telehealth for compounded GLP-1 weight loss programs, with one flat price at every dose.